A submucosal endoluminal method for the treatment of achalasia utilizing POEM has been developed as a result of advancements in natural orifice transluminal endoscopic surgery. Submucosal tunneling was initially introduced by Sumiyama et al. However, a preclinical experimental model was used to first explain the POEM idea in 2007. This study showed that executing a myotomy in 4 pigs under endoscopic vision following the construction of a submucosal tunnel was both safe and effective. when carried out by skilled endoscopists, according to numerous studies from Asia, Europe, and the United States. Furthermore, a recent white paper summary from the American Society of Gastrointestinal Endoscopy offered a wealth of information to back up the idea that POEM is a promising therapeutic approach. This review illustrates the patient selection and preparation, surgical method, clinical results, and POEM's future direction.
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